6Q00
TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1
Summary for 6Q00
Entry DOI | 10.2210/pdb6q00/pdb |
Descriptor | Ubiquitin, Tyrosyl-DNA phosphodiesterase 2, POTASSIUM ION, ... (4 entities in total) |
Functional Keywords | tdp2, dna damage response, cell signaling, post-translational modification, topoisomerase 2, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 13698.65 |
Authors | Schellenberg, M.J.,Krahn, J.M.,Williams, R.S. (deposition date: 2019-08-01, release date: 2020-04-29, Last modification date: 2020-06-24) |
Primary citation | Schellenberg, M.J.,Appel, C.D.,Riccio, A.A.,Butler, L.R.,Krahn, J.M.,Liebermann, J.A.,Cortes-Ledesma, F.,Williams, R.S. Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. Nucleic Acids Res., 48:6310-6325, 2020 Cited by PubMed: 32356875DOI: 10.1093/nar/gkaa318 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.85 Å) |
Structure validation
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