6Q00

TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1

Summary for 6Q00

• Entry DOI: 10.2210/pdb6q00/pdb
• Descriptor: Ubiquitin, Tyrosyl-DNA phosphodiesterase 2, POTASSIUM ION, ... (4 entities in total)
• Functional Keywords: tdp2, dna damage response, cell signaling, post-translational modification, topoisomerase 2, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 13698.65

Authors

Schellenberg, M.J.,Krahn, J.M.,Williams, R.S. (deposition date: 2019-08-01, release date: 2020-04-29, Last modification date: 2020-06-24)

• Primary citation: Schellenberg, M.J.,Appel, C.D.,Riccio, A.A.,Butler, L.R.,Krahn, J.M.,Liebermann, J.A.,Cortes-Ledesma, F.,Williams, R.S.; Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.; Nucleic Acids Res., 48:6310-6325, 2020; PubMed: 32356875; DOI: 10.1093/nar/gkaa318

Experimental method

X-RAY DIFFRACTION (0.85 Å)