6PZD

Crystal structure of the neuraminidase stabilization mutant Y169aH from A/Shanghai/2/2013 (H7N9)

6PZD の概要

• エントリーDOI: 10.2210/pdb6pzd/pdb
• 分子名称: Neuraminidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (7 entities in total)
• 機能のキーワード: antibody, inhibition mechanism, viral protein
• 由来する生物種: Influenza A virus (A/Shanghai/02/2013(H7N9))
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46502.39

構造登録者

Zhu, X.,Wilson, I.A. (登録日: 2019-07-31, 公開日: 2019-12-04, 最終更新日: 2023-10-11)

• 主引用文献: Zhu, X.,Turner, H.L.,Lang, S.,McBride, R.,Bangaru, S.,Gilchuk, I.M.,Yu, W.,Paulson, J.C.,Crowe Jr., J.E.,Ward, A.B.,Wilson, I.A.; Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.; Cell Host Microbe, 26:729-, 2019; PubMed: 31757767; DOI: 10.1016/j.chom.2019.10.002

実験手法

X-RAY DIFFRACTION (1.12 Å)