6PZC

Cryo-EM structure of the pancreatic beta-cell SUR1 bound to carbamazepine

Summary for 6PZC

Entry DOI	10.2210/pdb6pzc/pdb
EMDB information	20528 20530 20533 20534 20535
Descriptor	ATP-binding cassette sub-family C member 8 (1 entity in total)
Functional Keywords	katp, sur1, carbamazepine, membrane protein
Biological source	Cricetus cricetus (Black-bellied hamster)
Total number of polymer chains	1
Total formula weight	177333.58
Authors	Shyng, S.L.,Yoshioka, C.,Martin, G.M.,Sung, M.W. (deposition date: 2019-07-31, release date: 2019-08-14, Last modification date: 2024-03-20)
Primary citation	Martin, G.M.,Sung, M.W.,Yang, Z.,Innes, L.M.,Kandasamy, B.,David, L.L.,Yoshioka, C.,Shyng, S.L. Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8:-, 2019 Cited by PubMed: 31343405 DOI: 10.7554/eLife.46417 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.34 Å)

Structure validation