6PZ9

Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide

Summary for 6PZ9

• Entry DOI: 10.2210/pdb6pz9/pdb
• EMDB information: 20528 20530 20533 20534 20535
• Descriptor: ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, Repaglinide, ... (4 entities in total)
• Functional Keywords: katp, sur1, rpg, membrane protein
• Biological source: Cricetus cricetus (Black-bellied hamster); More
• Total number of polymer chains: 2
• Total formula weight: 221939.06

Authors

Shyng, S.L.,Yoshioka, C.,Martin, G.M.,Sung, M.W. (deposition date: 2019-07-31, release date: 2019-08-14, Last modification date: 2024-03-20)

• Primary citation: Martin, G.M.,Sung, M.W.,Yang, Z.,Innes, L.M.,Kandasamy, B.,David, L.L.,Yoshioka, C.,Shyng, S.L.; Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.; Elife, 8:-, 2019; PubMed: 31343405; DOI: 10.7554/eLife.46417

Experimental method

ELECTRON MICROSCOPY (3.65 Å)