6PYV

Crystal Structure of HLA-B*2703-P47G in complex with LRN, a self-peptide

Summary for 6PYV

• Entry DOI: 10.2210/pdb6pyv/pdb
• Descriptor: HLA class I histocompatibility antigen, B-2703 alpha chain, Beta-2-microglobulin, LRN peptide, ... (4 entities in total)
• Functional Keywords: ankylosing spondylitis, hla-b27, hla-b*27:05, hla-b*27:03, hla, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 44736.49

Authors

Gras, S. (deposition date: 2019-07-31, release date: 2019-11-27, Last modification date: 2023-10-11)

• Primary citation: Lim Kam Sian, T.C.C.,Indumathy, S.,Halim, H.,Greule, A.,Cryle, M.J.,Bowness, P.,Rossjohn, J.,Gras, S.,Purcell, A.W.,Schittenhelm, R.B.; Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.; J.Biol.Chem., 294:20185-20195, 2019; PubMed: 31740583; DOI: 10.1074/jbc.RA119.010257

Experimental method

X-RAY DIFFRACTION (1.45 Å)