6PXH

Crystal Structure of MERS-CoV S1-NTD bound with G2 Fab

6PXH の概要

• エントリーDOI: 10.2210/pdb6pxh/pdb
• 分子名称: MERS-CoV S1-NTD, DIHYDROFOLIC ACID, G2 heavy chain, ... (11 entities in total)
• 機能のキーワード: immune system, antibody, fusion glycoprotein, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Middle East respiratory syndrome-related coronavirus; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 182341.99

構造登録者

Wang, N.,McLellan, J.S. (登録日: 2019-07-26, 公開日: 2019-09-25, 最終更新日: 2020-07-29)

• 主引用文献: Wang, N.,Rosen, O.,Wang, L.,Turner, H.L.,Stevens, L.J.,Corbett, K.S.,Bowman, C.A.,Pallesen, J.,Shi, W.,Zhang, Y.,Leung, K.,Kirchdoerfer, R.N.,Becker, M.M.,Denison, M.R.,Chappell, J.D.,Ward, A.B.,Graham, B.S.,McLellan, J.S.; Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.; Cell Rep, 28:3395-3405.e6, 2019; PubMed: 31553909; DOI: 10.1016/j.celrep.2019.08.052

実験手法

X-RAY DIFFRACTION (2.3 Å)