6PWM

ADC-7 in complex with Beta-lactam antibiotic ceftazidime

6PWM の概要

• エントリーDOI: 10.2210/pdb6pwm/pdb
• 分子名称: Beta-lactamase, ACYLATED CEFTAZIDIME, GLYCINE, ... (4 entities in total)
• 機能のキーワード: substrate, beta-lactamase, antibiotic, adc-7., hydrolase
• 由来する生物種: Acinetobacter baumannii
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 165187.02

構造登録者

Curtis, B.C.,Powers, R.A.,Wallar, B.J. (登録日: 2019-07-23, 公開日: 2020-10-21, 最終更新日: 2023-10-11)

• 主引用文献: Curtis, B.N.,Smolen, K.A.,Barlow, S.J.,Caselli, E.,Prati, F.,Taracila, M.A.,Bonomo, R.A.,Wallar, B.J.,Powers, R.A.; Structural Insights into Inhibition of the Acinetobacter-Derived Cephalosporinase ADC-7 by Ceftazidime and Its Boronic Acid Transition State Analog.; Antimicrob.Agents Chemother., 64:-, 2020; PubMed: 32988830; DOI: 10.1128/AAC.01183-20

実験手法

X-RAY DIFFRACTION (2.4 Å)