6PT2
Crystal structure of the active delta opioid receptor in complex with the peptide agonist KGCHM07
Summary for 6PT2
Entry DOI | 10.2210/pdb6pt2/pdb |
Descriptor | Delta opioid receptor, Peptide agonist KGCHM07, CHOLESTEROL, ... (6 entities in total) |
Functional Keywords | membrane protein, g protein-coupled receptor, gpcr, dop, dor, peptide agonist, active dop-kgchm07 structure, lcp, membrane protein-agonist complex, membrane protein/agonist |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 106486.31 |
Authors | Claff, T.,Yu, J.,Blais, V.,Patel, N.,Martin, C.,Wu, L.,Han, G.W.,Holleran, B.J.,Van der Poorten, O.,Hanson, M.A.,Sarret, P.,Gendron, L.,Cherezov, V.,Katritch, V.,Ballet, S.,Liu, Z.,Muller, C.E.,Stevens, R.C. (deposition date: 2019-07-14, release date: 2019-12-11, Last modification date: 2023-11-15) |
Primary citation | Claff, T.,Yu, J.,Blais, V.,Patel, N.,Martin, C.,Wu, L.,Han, G.W.,Holleran, B.J.,Van der Poorten, O.,White, K.L.,Hanson, M.A.,Sarret, P.,Gendron, L.,Cherezov, V.,Katritch, V.,Ballet, S.,Liu, Z.J.,Muller, C.E.,Stevens, R.C. Elucidating the active delta-opioid receptor crystal structure with peptide and small-molecule agonists. Sci Adv, 5:eaax9115-eaax9115, 2019 Cited by PubMed: 31807708DOI: 10.1126/sciadv.aax9115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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