6PT2

Crystal structure of the active delta opioid receptor in complex with the peptide agonist KGCHM07

6PT2 の概要

• エントリーDOI: 10.2210/pdb6pt2/pdb
• 分子名称: Delta opioid receptor, Peptide agonist KGCHM07, CHOLESTEROL, ... (6 entities in total)
• 機能のキーワード: membrane protein, g protein-coupled receptor, gpcr, dop, dor, peptide agonist, active dop-kgchm07 structure, lcp, membrane protein-agonist complex, membrane protein/agonist
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 106486.31

構造登録者

Claff, T.,Yu, J.,Blais, V.,Patel, N.,Martin, C.,Wu, L.,Han, G.W.,Holleran, B.J.,Van der Poorten, O.,Hanson, M.A.,Sarret, P.,Gendron, L.,Cherezov, V.,Katritch, V.,Ballet, S.,Liu, Z.,Muller, C.E.,Stevens, R.C. (登録日: 2019-07-14, 公開日: 2019-12-11, 最終更新日: 2023-11-15)

• 主引用文献: Claff, T.,Yu, J.,Blais, V.,Patel, N.,Martin, C.,Wu, L.,Han, G.W.,Holleran, B.J.,Van der Poorten, O.,White, K.L.,Hanson, M.A.,Sarret, P.,Gendron, L.,Cherezov, V.,Katritch, V.,Ballet, S.,Liu, Z.J.,Muller, C.E.,Stevens, R.C.; Elucidating the active delta-opioid receptor crystal structure with peptide and small-molecule agonists.; Sci Adv, 5:eaax9115-eaax9115, 2019; PubMed: 31807708; DOI: 10.1126/sciadv.aax9115

実験手法

X-RAY DIFFRACTION (2.8 Å)