6PT0
Cryo-EM structure of human cannabinoid receptor 2-Gi protein in complex with agonist WIN 55,212-2
Summary for 6PT0
Entry DOI | 10.2210/pdb6pt0/pdb |
EMDB information | 20470 |
Descriptor | Cannabinoid receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (8 entities in total) |
Functional Keywords | gpcr complex, win55, 212-2, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 158678.19 |
Authors | Xu, T.H.,Xing, C.,Zhuang, Y.,Feng, Z.,Zhou, X.E.,Chen, M.,Wang, L.,Meng, X.,Xue, Y.,Wang, J.,Liu, H.,McGuire, T.,Zhao, G.,Melcher, K.,Zhang, C.,Xu, H.E.,Xie, X.Q. (deposition date: 2019-07-14, release date: 2020-02-12, Last modification date: 2020-03-04) |
Primary citation | Xing, C.,Zhuang, Y.,Xu, T.H.,Feng, Z.,Zhou, X.E.,Chen, M.,Wang, L.,Meng, X.,Xue, Y.,Wang, J.,Liu, H.,McGuire, T.F.,Zhao, G.,Melcher, K.,Zhang, C.,Xu, H.E.,Xie, X.Q. Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex. Cell, 180:645-, 2020 Cited by PubMed: 32004460DOI: 10.1016/j.cell.2020.01.007 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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