6PLA

Adducts formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)osmium(II) with HEWL

6PLA の概要

• エントリーDOI: 10.2210/pdb6pla/pdb
• 分子名称: Lysozyme, SODIUM ION, dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)osmium(II), ... (5 entities in total)
• 機能のキーワード: metal-based, anticancer, ruthenium, nhc, carbene, lysozyme, metallodrug, benzimidazole, dimethylbenzimidazole, hydrolase
• 由来する生物種: Gallus gallus (Chicken)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15619.40

構造登録者

Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (登録日: 2019-06-30, 公開日: 2020-11-25, 最終更新日: 2023-10-11)

• 主引用文献: Sullivan, M.P.,Cziferszky, M.,Tolbatov, I.,Truong, D.,Mercadante, D.,Re, N.,Gust, R.,Goldstone, D.C.,Hartinger, C.; Probing the Paradigm of Promiscuity for N-Heterocyclic Carbene Complexes and their Protein Adduct Formation.; Angew.Chem.Int.Ed.Engl., 2021; PubMed: 34196088; DOI: 10.1002/anie.202106906

実験手法

X-RAY DIFFRACTION (1.25 Å)