6PKW

Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C2 symmetry (pseudo C4 symmetry)

Summary for 6PKW

Entry DOI	10.2210/pdb6pkw/pdb
EMDB information	20367 20368 20369
Descriptor	Transient receptor potential cation channel subfamily M member 2 (1 entity in total)
Functional Keywords	warmth sensor, redox sensor, calcium-permeable ion channel, trp channel, trpm channel, ion channel, adp-ribose, transport protein
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	4
Total formula weight	670434.50
Authors	Yin, Y.,Wu, M.,Hsu, A.L.,Borschel, W.F.,Borgnia, M.J.,Lander, G.C.,Lee, S.-Y. (deposition date: 2019-06-30, release date: 2019-08-28, Last modification date: 2024-03-20)
Primary citation	Yin, Y.,Wu, M.,Hsu, A.L.,Borschel, W.F.,Borgnia, M.J.,Lander, G.C.,Lee, S.Y. Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel. Nat Commun, 10:3740-3740, 2019 Cited by PubMed: 31431622 DOI: 10.1038/s41467-019-11733-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.5 Å)

Structure validation