6PK2

CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS

6PK2 の概要

• エントリーDOI: 10.2210/pdb6pk2/pdb
• 分子名称: Propionyl-CoA carboxylase subunit beta, 2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide (3 entities in total)
• 機能のキーワード: crotonase super family, carboxyltransferase, transferase-herbicide, structural genomics, transferase, psi-biology, protein structure initiative, tb structural genomics consortium, tbsgc
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 404250.26

構造登録者

Reddy, M.C.M.,Nian, Z.,Michele, T.C.B.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2019-06-28, 公開日: 2020-07-01, 最終更新日: 2024-03-13)

• 主引用文献: Reddy, M.C.M.,Nian, Z.,Sacchettini, J.C.; Elucidating the Inhibition and specificity of binding of herbicidal aryloxyphenoxypropionates derivatives to Mycobacterium tuberculosis carboxyltransferase domain of acetyl-coenzyme A(AccD6).; To Be Published,

実験手法

X-RAY DIFFRACTION (2.402 Å)