6PDX

Crystal structure of C585 Fab in complex with influenza virus hemagglutinin from A/Switzerland/9715293/2013 (H3N2)

6PDX の概要

• エントリーDOI: 10.2210/pdb6pdx/pdb
• 分子名称: Hemagglutinin, C585 Fab heavy chain, C585 Fab light chain, ... (6 entities in total)
• 機能のキーワード: influenza virus, hemagglutinin, broadly neutralizing antibody, h3n2, viral protein, immune system
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 324143.14

構造登録者

Qiu, Y.,Zhou, Y. (登録日: 2019-06-19, 公開日: 2019-12-18, 最終更新日: 2020-07-29)

• 主引用文献: Qiu, Y.,Stegalkina, S.,Zhang, J.,Boudanova, E.,Park, A.,Zhou, Y.,Prabakaran, P.,Pougatcheva, S.,Ustyugova, I.V.,Vogel, T.U.,Mundle, S.T.,Oomen, R.,Delagrave, S.,Ross, T.M.,Kleanthous, H.,Qiu, H.; Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth.; J.Virol., 94:-, 2020; PubMed: 31826999; DOI: 10.1128/JVI.01035-19

実験手法

X-RAY DIFFRACTION (3.993 Å)