6PDQ

Ancestral Effector Caspase 3/6/7

Summary for 6PDQ

Entry DOI	10.2210/pdb6pdq/pdb
Descriptor	Ancestral Effector Caspase-3/6/7, Ac-DEVD inhibitor, ... (4 entities in total)
Functional Keywords	ancestral effector caspase, protease, ancestral protein reconstruction, apoptosis
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	54269.16
Authors	Clark, A.C. (deposition date: 2019-06-19, release date: 2019-11-13, Last modification date: 2020-01-01)
Primary citation	Grinshpon, R.D.,Shrestha, S.,Titus-McQuillan, J.,Hamilton, P.T.,Swartz, P.D.,Clark, A.C. Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity. Biochem.J., 476:3475-3492, 2019 Cited by PubMed: 31675069 DOI: 10.1042/BCJ20190625 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.83 Å)

Structure validation