6PCW

Human PIM1 bound to benzothiophene inhibitor 213

6PCW の概要

• エントリーDOI: 10.2210/pdb6pcw/pdb
• 分子名称: Serine/threonine-protein kinase pim-1, Peptide, 4-[5-(cyclopropylcarbamoyl)thiophen-2-yl]-1-benzothiophene-2-carboxamide, ... (5 entities in total)
• 機能のキーワード: proto-oncogene serine/threonine-protein kinase pim-1, structural genomics, structural genomics consortium, sgc, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37709.97

構造登録者

Godoi, P.H.C.,Santiago, A.S.,Fala, A.M.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M.,Structural Genomics Consortium (SGC) (登録日: 2019-06-18, 公開日: 2019-07-24, 最終更新日: 2023-10-11)

• 主引用文献: Godoi, P.H.C.,Santiago, A.S.,Fala, A.M.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M.; PIM1 bound to benzothiophene inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)