6P99

OXA-48 carbapanemase, ertapenem complex

6P99 の概要

• エントリーDOI: 10.2210/pdb6p99/pdb
• 分子名称: Beta-lactamase, (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: antibiotic resistance, beta-lactamase, carbapenemase, ertapenem complex, hydrolase-antibiotic complex, hydrolase/antibiotic
• 由来する生物種: Klebsiella pneumoniae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61834.80

構造登録者

Smith, C.A.,Vakulenko, S.B. (登録日: 2019-06-10, 公開日: 2019-08-07, 最終更新日: 2024-03-13)

• 主引用文献: Smith, C.A.,Stewart, N.K.,Toth, M.,Vakulenko, S.B.; Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase.; Antimicrob.Agents Chemother., 63:-, 2019; PubMed: 31358584; DOI: 10.1128/AAC.01202-19

実験手法

X-RAY DIFFRACTION (2.25 Å)