6P97
OXA-48 carbapanemase, imipenem complex
Summary for 6P97
Entry DOI | 10.2210/pdb6p97/pdb |
Descriptor | Beta-lactamase, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | antibiotic resistance, beta-lactamase, carbapenemase, imipenem complex, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 61923.11 |
Authors | Smith, C.A.,Vakulenko, S.B. (deposition date: 2019-06-10, release date: 2019-08-07, Last modification date: 2019-10-09) |
Primary citation | Smith, C.A.,Stewart, N.K.,Toth, M.,Vakulenko, S.B. Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase. Antimicrob.Agents Chemother., 63:-, 2019 Cited by PubMed: 31358584DOI: 10.1128/AAC.01202-19 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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