6P90

Crystal structure of PaDHDPS2-H56Q mutant

6P90 の概要

• エントリーDOI: 10.2210/pdb6p90/pdb
• 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: allosteric regulation, antibiotic resistance, diaminopimelate, 4-hydroxy-tetrahydrodipicolinate synthase, lysine biosynthesis, structural protein
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63205.68

構造登録者

Impey, R.E.,Panjikar, S.,Hall, C.J.,Bock, L.J.,Sutton, J.M.,Perugini, M.A.,Soares da Costa, T.P. (登録日: 2019-06-08, 公開日: 2019-08-07, 最終更新日: 2023-10-11)

• 主引用文献: Impey, R.E.,Panjikar, S.,Hall, C.J.,Bock, L.J.,Sutton, J.M.,Perugini, M.A.,Soares da Costa, T.P.; Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation.; Febs J., 287:386-400, 2020; PubMed: 31330085; DOI: 10.1111/febs.15014

実験手法

X-RAY DIFFRACTION (1.9 Å)