6P8T

Acinetobacter baumannii tRNA synthetase in complex with compound 1

6P8T の概要

• エントリーDOI: 10.2210/pdb6p8t/pdb
• 分子名称: Phenylalanine--tRNA ligase beta subunit, Phenylalanine--tRNA ligase alpha subunit, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: inhibitor, aminoacyl-trna synthetase, phers, antibacterial, ligase
• 由来する生物種: Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / CIP 70.34 / JCM 6841 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 500977.78

構造登録者

Kahne, D.,Baidin, V.,Owens, T.W. (登録日: 2019-06-07, 公開日: 2020-11-18, 最終更新日: 2023-10-11)

• 主引用文献: Baidin, V.,Owens, T.W.,Lazarus, M.B.,Kahne, D.; Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase.; J.Am.Chem.Soc., 143:623-627, 2021; PubMed: 33411531; DOI: 10.1021/jacs.0c11113

実験手法

X-RAY DIFFRACTION (3.15 Å)