6P6W
Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state
Summary for 6P6W
Entry DOI | 10.2210/pdb6p6w/pdb |
EMDB information | 20265 |
Descriptor | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb (1 entity in total) |
Functional Keywords | ion channel, ion transport protein, membrane protein, metal transport |
Biological source | Escherichia coli K-12 More |
Total number of polymer chains | 4 |
Total formula weight | 296291.19 |
Authors | Wisedchaisri, G.,Tonggu, L.,McCord, E.,Gamal El-Din, T.M.,Wang, L.,Zheng, N.,Catterall, W.A. (deposition date: 2019-06-04, release date: 2019-08-14, Last modification date: 2019-12-18) |
Primary citation | Wisedchaisri, G.,Tonggu, L.,McCord, E.,Gamal El-Din, T.M.,Wang, L.,Zheng, N.,Catterall, W.A. Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178:993-, 2019 Cited by PubMed: 31353218DOI: 10.1016/j.cell.2019.06.031 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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