6P55

Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae acylated by cefixime

6P55 の概要

• エントリーDOI: 10.2210/pdb6p55/pdb
• 分子名称: peptidoglycan D,D-transpeptidase PenA, cefixime, bound form, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: penicillin-binding protein, transpeptidase domain, neisseria gonorrhoeae, antibiotic resistance, hydrolase-antibiotic complex, hydrolase/antibiotic
• 由来する生物種: Neisseria gonorrhoeae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72166.73

構造登録者

Singh, A.,Davies, C. (登録日: 2019-05-29, 公開日: 2019-08-07, 最終更新日: 2020-01-01)

• 主引用文献: Singh, A.,Tomberg, J.,Nicholas, R.A.,Davies, C.; Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.; J.Biol.Chem., 294:14020-14032, 2019; PubMed: 31362987; DOI: 10.1074/jbc.RA119.009942

実験手法

X-RAY DIFFRACTION (1.74 Å)