6P4Z

Structure of gadolinium-caged cobalt (III) insulin hexamer

Summary for 6P4Z

DescriptorInsulin chain A, Insulin chain B, COBALT (II) ION, ... (6 entities in total)
Functional Keywordscontrast agent, environmentally sensitive, gadolinium, insulin hexamer, proteins, hormone
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight11945.87
Authors
Tran, T.H.,Taylor, S.K.,Stojanovic, M.N.,Tong, L. (deposition date: 2019-05-29, release date: 2019-06-12, Last modification date: 2019-06-19)
Primary citation
Taylor, S.K.,Tran, T.H.,Liu, M.Z.,Harris, P.E.,Sun, Y.,Jambawalikar, S.R.,Tong, L.,Stojanovic, M.N.
Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore
ChemBioChem, 24:10646-10652, 2018
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.238600 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution