6P2S

Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing and presentation

6P2S の概要

• エントリーDOI: 10.2210/pdb6p2s/pdb
• 分子名称: MHC class I antigen, Beta-2-microglobulin, MHC I-peptide, ... (4 entities in total)
• 機能のキーワード: mhc i antigen processing, mhc i antigen presentation, mhc i structure, mhc i immunopeptide, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45021.92

構造登録者

Li, L.,Batliwala, M.,Bouvier, M. (登録日: 2019-05-22, 公開日: 2019-10-16, 最終更新日: 2023-10-25)

• 主引用文献: Li, L.,Batliwala, M.,Bouvier, M.; ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.; J.Biol.Chem., 294:18534-18544, 2019; PubMed: 31601650; DOI: 10.1074/jbc.RA119.010102

実験手法

X-RAY DIFFRACTION (1.65 Å)