6P1Y
Crystal structure of Mtb aspartate decarboxylase mutant M117I
Summary for 6P1Y
Entry DOI | 10.2210/pdb6p1y/pdb |
Descriptor | Aspartate 1-decarboxylase beta chain, Aspartate 1-decarboxylase alpha chain, AMMONIUM ION, ... (5 entities in total) |
Functional Keywords | structural genomics, tb structural genomics consortium, tbsgc, lyase, poa, drug-resistance, mutant |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More |
Total number of polymer chains | 2 |
Total formula weight | 16123.20 |
Authors | Sun, Q.,Li, X.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2019-05-20, release date: 2020-02-05, Last modification date: 2023-11-15) |
Primary citation | Sun, Q.,Li, X.,Perez, L.M.,Shi, W.,Zhang, Y.,Sacchettini, J.C. The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nat Commun, 11:339-339, 2020 Cited by PubMed: 31953389DOI: 10.1038/s41467-019-14238-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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