6P1Y

Crystal structure of Mtb aspartate decarboxylase mutant M117I

6P1Y の概要

• エントリーDOI: 10.2210/pdb6p1y/pdb
• 分子名称: Aspartate 1-decarboxylase beta chain, Aspartate 1-decarboxylase alpha chain, AMMONIUM ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, tb structural genomics consortium, tbsgc, lyase, poa, drug-resistance, mutant
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 16123.20

構造登録者

Sun, Q.,Li, X.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2019-05-20, 公開日: 2020-02-05, 最終更新日: 2023-11-15)

• 主引用文献: Sun, Q.,Li, X.,Perez, L.M.,Shi, W.,Zhang, Y.,Sacchettini, J.C.; The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD.; Nat Commun, 11:339-339, 2020; PubMed: 31953389; DOI: 10.1038/s41467-019-14238-3

実験手法

X-RAY DIFFRACTION (2.33 Å)