6P1K

Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme

Summary for 6P1K

Entry DOI	10.2210/pdb6p1k/pdb
EMDB information	20230
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total)
Functional Keywords	protein-dna complex, transcription initiation, rna polyermase, dna promoter melting, transcription
Biological source	Escherichia coli More
Total number of polymer chains	6
Total formula weight	463132.12
Authors	Chen, J.,Chiu, C.E.,Campbell, E.A.,Darst, S.A. (deposition date: 2019-05-20, release date: 2020-02-26, Last modification date: 2024-03-13)
Primary citation	Chen, J.,Gopalkrishnan, S.,Chiu, C.,Chen, A.Y.,Campbell, E.A.,Gourse, R.L.,Ross, W.,Darst, S.A. E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8:-, 2019 Cited by PubMed: 31841111 DOI: 10.7554/eLife.49375 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.05 Å)

Structure validation