6OZE

Crystal structure of the catalytic domain of human Endonuclease V (C140S/C225S/C226A/C228S)

Summary for 6OZE

Entry DOI	10.2210/pdb6oze/pdb
Descriptor	Endonuclease V, ACETATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	nucleic acid hydrolysis, rna recognition, metal ion dependent catalysis, dna damage, adenosine deamination, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	27505.61
Authors	Samara, N.L.,Yang, W. (deposition date: 2019-05-15, release date: 2019-09-04, Last modification date: 2023-10-11)
Primary citation	Wu, J.,Samara, N.L.,Kuraoka, I.,Yang, W. Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76:44-, 2019 Cited by PubMed: 31444105 DOI: 10.1016/j.molcel.2019.06.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation