6OY8
Crystal structure of Y99G mutant of human macrophage migration inhibitory factor
Summary for 6OY8
Entry DOI | 10.2210/pdb6oy8/pdb |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ... (5 entities in total) |
Functional Keywords | isomerase, trimeric, mutation |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 37523.56 |
Authors | Pantouris, G.,Lolis, E. (deposition date: 2019-05-14, release date: 2020-04-22, Last modification date: 2023-10-11) |
Primary citation | Pantouris, G.,Khurana, L.,Ma, A.,Skeens, E.,Reiss, K.,Batista, V.S.,Lisi, G.P.,Lolis, E.J. Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27:740-750.e5, 2020 Cited by PubMed: 32433911DOI: 10.1016/j.chembiol.2020.05.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
Download full validation report