Horse liver F93W alcohol dehydrogenase complexed with NAD and trifluoroethanol

Summary for 6OWP

Related4DXH 6OWM 1AXE 1A71 5KCZ 6OA7
DescriptorAlcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
Functional Keywords2, alcohol dehydrogenase, nad, 2-trifluoretanol, phe93 to trp substitution, horse liver e enzyme, oxidoreductase
Biological sourceEquus caballus (Horse)
Total number of polymer chains2
Total molecular weight81927.71
Plapp, B.V. (deposition date: 2019-05-10, release date: 2019-05-22)
Primary citation
Plapp, B.V.,Kim, K.
Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.14510 0.3% 0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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