6OWP
Horse liver F93W alcohol dehydrogenase complexed with NAD and trifluoroethanol
Summary for 6OWP
Entry DOI | 10.2210/pdb6owp/pdb |
Related | 1A71 1AXE 4DXH 5KCZ 6OA7 6OWM |
Descriptor | Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total) |
Functional Keywords | alcohol dehydrogenase, nad, 2, 2-trifluoretanol, phe93 to trp substitution, horse liver e enzyme, oxidoreductase |
Biological source | Equus caballus (Horse) |
Total number of polymer chains | 2 |
Total formula weight | 81927.71 |
Authors | Plapp, B.V. (deposition date: 2019-05-10, release date: 2019-05-22, Last modification date: 2023-10-11) |
Primary citation | Kim, K.,Plapp, B.V. Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer. Biochemistry, 59:862-879, 2020 Cited by PubMed: 31994873DOI: 10.1021/acs.biochem.9b01074 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.14 Å) |
Structure validation
Download full validation report