6OVT

Crystal Structure of IlvD from Mycobacterium tuberculosis

6OVT の概要

• エントリーDOI: 10.2210/pdb6ovt/pdb
• 分子名称: Dihydroxy-acid dehydratase, MAGNESIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... (6 entities in total)
• 機能のキーワード: dihydroxy-acid dehydratase 2, 3-dihydroxy-3-methylbutanoate 3-methyl-2-oxobutanoate, lyase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 251575.68

構造登録者

Almo, S.C.,Grove, T.L.,Bonanno, J.B.,Baker, E.N.,Bashiri, G. (登録日: 2019-05-08, 公開日: 2019-08-07, 最終更新日: 2019-12-18)

• 主引用文献: Bashiri, G.,Grove, T.L.,Hegde, S.S.,Lagautriere, T.,Gerfen, G.J.,Almo, S.C.,Squire, C.J.,Blanchard, J.S.,Baker, E.N.; The active site of theMycobacterium tuberculosisbranched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.; J.Biol.Chem., 294:13158-13170, 2019; PubMed: 31315931; DOI: 10.1074/jbc.RA119.009498

実験手法

X-RAY DIFFRACTION (1.88 Å)