6OU1

Crystal Structure of the Computationally-derived 21-Variant of the Myocilin Olfactomedin Domain

6OU1 の概要

• エントリーDOI: 10.2210/pdb6ou1/pdb
• 分子名称: Myocilin, CALCIUM ION, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: olfactomedin myocilin beta propeller, protein binding
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63018.46

構造登録者

Hill, S.E.,Kwon, M.S.,Lieberman, R.L. (登録日: 2019-05-03, 公開日: 2019-07-03, 最終更新日: 2020-01-15)

• 主引用文献: Hill, S.E.,Kwon, M.S.,Martin, M.D.,Suntharalingam, A.,Hazel, A.,Dickey, C.A.,Gumbart, J.C.,Lieberman, R.L.; Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations.; J.Biol.Chem., 294:12717-12728, 2019; PubMed: 31270212; DOI: 10.1074/jbc.RA119.009419

実験手法

X-RAY DIFFRACTION (1.878 Å)