6OTN

Crystal Structure of an N-terminal Fragment of Cancer Associated Tropomyosin 3.1 (Tpm3.1)

6OTN の概要

• エントリーDOI: 10.2210/pdb6otn/pdb
• 分子名称: Tropomyosin alpha-3 chain, SULFATE ION (3 entities in total)
• 機能のキーワード: tropomyosin, fragment, coiled coil, structural protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 37237.27

構造登録者

Rynkiewicz, M.J.,Ghosh, A.,Lehman, W.J.,Janco, M.,Gunning, P.W. (登録日: 2019-05-03, 公開日: 2019-08-14, 最終更新日: 2023-10-11)

• 主引用文献: Janco, M.,Rynkiewicz, M.J.,Li, L.,Hook, J.,Eiffe, E.,Ghosh, A.,Bocking, T.,Lehman, W.J.,Hardeman, E.C.,Gunning, P.W.; Molecular integration of the anti-tropomyosin compound ATM-3507 into the coiled coil overlap region of the cancer-associated Tpm3.1.; Sci Rep, 9:11262-11262, 2019; PubMed: 31375704; DOI: 10.1038/s41598-019-47592-9

実験手法

X-RAY DIFFRACTION (2.4 Å)