6OSA

human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in non-canonical conformation (NC state)

Summary for 6OSA

Entry DOI	10.2210/pdb6osa/pdb
EMDB information	20180 20181
Descriptor	Neurotensin receptor type 1, JMV449, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (5 entities in total)
Functional Keywords	gpcr, g-protein, complex, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	135106.99
Authors	Kato, H.E.,Zhang, Y.,Kobilka, B.K.,Skiniotis, G. (deposition date: 2019-05-01, release date: 2019-07-10, Last modification date: 2019-12-18)
Primary citation	Kato, H.E.,Zhang, Y.,Hu, H.,Suomivuori, C.M.,Kadji, F.M.N.,Aoki, J.,Krishna Kumar, K.,Fonseca, R.,Hilger, D.,Huang, W.,Latorraca, N.R.,Inoue, A.,Dror, R.O.,Kobilka, B.K.,Skiniotis, G. Conformational transitions of a neurotensin receptor 1-Gi1complex. Nature, 572:80-85, 2019 Cited by PubMed: 31243364 DOI: 10.1038/s41586-019-1337-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation