6OM7
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
This is a non-PDB format compatible entry.
Summary for 6OM7
Entry DOI | 10.2210/pdb6om7/pdb |
EMDB information | 0526 0596 0597 0598 0599 0600 0601 |
Descriptor | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S15, ... (87 entities in total) |
Functional Keywords | selective stalling, drug-like small molecule, human ribosome nascent chain complex, ribosome |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 83 |
Total formula weight | 3182622.08 |
Authors | Li, W.,Cate, J.H.D. (deposition date: 2019-04-18, release date: 2019-06-19, Last modification date: 2019-12-18) |
Primary citation | Li, W.,Ward, F.R.,McClure, K.F.,Chang, S.T.,Montabana, E.,Liras, S.,Dullea, R.G.,Cate, J.H.D. Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26:501-509, 2019 Cited by PubMed: 31160784DOI: 10.1038/s41594-019-0236-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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