6OM4

The structure of Microcin C7 biosynthetic enzyme MccB in complex with N-formylated MccA

Summary for 6OM4

DescriptorMccB protein, Microcin C7, ZINC ION, ... (7 entities in total)
Functional Keywordsmicrocin c7, phosphoramidate, trojan horse antibiotic, biosynthetic protein
Biological sourceEscherichia coli
Total number of polymer chains4
Total molecular weight80564.36
Authors
Dong, S.-H.,Nair, S.K. (deposition date: 2019-04-18, release date: 2019-05-22)
Primary citation
Dong, S.H.,Kulikovsky, A.,Zukher, I.,Estrada, P.,Dubiley, S.,Severinov, K.,Nair, S.K.
Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by theN-formyl of the peptide precursor.
Chem Sci, 10:2391-2395, 2019
PubMed: 30881667 (PDB entries with the same primary citation)
DOI: 10.1039/c8sc03173h
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20660 4.8% 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution