6OL7

Crystal structure of glVRC01 scFv in complex with anti-idiotype iv8 scFv

Summary for 6OL7

• Entry DOI: 10.2210/pdb6ol7/pdb
• Descriptor: iv8 Heavy Chain, glVRC01 Light Chain, glVRC01 Heavy Chain, ... (8 entities in total)
• Functional Keywords: glvrc01, iv8, anti-idiotype, scfv, antibody, hiv, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 16
• Total formula weight: 223425.73

Authors

Weidle, C.,Pancera, M. (deposition date: 2019-04-15, release date: 2019-07-24, Last modification date: 2023-10-11)

• Primary citation: Dosenovic, P.,Pettersson, A.K.,Wall, A.,Thientosapol, E.S.,Feng, J.,Weidle, C.,Bhullar, K.,Kara, E.E.,Hartweger, H.,Pai, J.A.,Gray, M.D.,Parks, K.R.,Taylor, J.J.,Pancera, M.,Stamatatos, L.,Nussenzweig, M.C.,McGuire, A.T.; Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.; J.Exp.Med., 216:2316-2330, 2019; PubMed: 31345931; DOI: 10.1084/jem.20190446

Experimental method

X-RAY DIFFRACTION (2.419 Å)