6OKN

OX40R (TNFRSF4) bound to Fab 1A7

Summary for 6OKN

Entry DOI	10.2210/pdb6okn/pdb
Related	6OGX
Descriptor	Fab 1A7 heavy chain, Fab 1A7 light chain, Tumor necrosis factor receptor superfamily member 4, ... (5 entities in total)
Functional Keywords	tnfrsf4, cd134, ox40r, fab, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	131585.00
Authors	Ultsch, M.H.,Boenig, G.,Harris, S.F. (deposition date: 2019-04-14, release date: 2019-07-10, Last modification date: 2019-08-14)
Primary citation	Yang, Y.,Yeh, S.H.,Madireddi, S.,Matochko, W.L.,Gu, C.,Pacheco Sanchez, P.,Ultsch, M.,De Leon Boenig, G.,Harris, S.F.,Leonard, B.,Scales, S.J.,Zhu, J.W.,Christensen, E.,Hang, J.Q.,Brezski, R.J.,Marsters, S.,Ashkenazi, A.,Sukumaran, S.,Chiu, H.,Cubas, R.,Kim, J.M.,Lazar, G.A. Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members. Mabs, 11:996-1011, 2019 Cited by PubMed: 31156033 DOI: 10.1080/19420862.2019.1625662 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation