6OJP

Structure of glycolipid alpha-GSA[8,6P] in complex with mouse CD1d

Summary for 6OJP

• Entry DOI: 10.2210/pdb6ojp/pdb
• Descriptor: Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: glycolipid-antigen presentation, mhc-fold, ig-fold, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 48053.89

Authors

Zajonc, D.M.,Bitra, A. (deposition date: 2019-04-11, release date: 2019-08-21, Last modification date: 2023-10-11)

• Primary citation: Wang, J.,Guillaume, J.,Janssens, J.,Remesh, S.G.,Ying, G.,Bitra, A.,Van Calenbergh, S.,Zajonc, D.M.; A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.; J.Biol.Chem., 294:14345-14356, 2019; PubMed: 31391251; DOI: 10.1074/jbc.RA119.009963

Experimental method

X-RAY DIFFRACTION (2.17 Å)