6OHU

Structure of EBP and tamoxifen

Summary for 6OHU

• Entry DOI: 10.2210/pdb6ohu/pdb
• Descriptor: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase, (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE (2 entities in total)
• Functional Keywords: membrane protein, isomerase, isomerase-inhibitor complex, isomerase/inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 83380.16

Authors

Long, T.,Li, X. (deposition date: 2019-04-06, release date: 2019-06-19, Last modification date: 2024-03-13)

• Primary citation: Long, T.,Hassan, A.,Thompson, B.M.,McDonald, J.G.,Wang, J.,Li, X.; Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition.; Nat Commun, 10:2452-2452, 2019; PubMed: 31165728; DOI: 10.1038/s41467-019-10279-w

Experimental method

X-RAY DIFFRACTION (3.526 Å)