6OHU

Structure of EBP and tamoxifen

6OHU の概要

分子名称3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase, (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE (2 entities in total)
機能のキーワードmembrane protein, isomerase, isomerase-inhibitor complex, isomerase/inhibitor
由来する生物種Homo sapiens (Human)
ポリマー鎖数3
分子量合計83380.16
構造登録者
Long, T.,Li, X. (登録日: 2019-04-06, 公開日: 2019-06-19)
主引用文献
Long, T.,Hassan, A.,Thompson, B.M.,McDonald, J.G.,Wang, J.,Li, X.
Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition.
Nat Commun, 10:2452-2452, 2019
PubMed: 31165728 (主引用文献が同じPDBエントリー)
DOI: 10.1038/s41467-019-10279-w
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (3.526 Å)
?

構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.32616 0.2% 5.9% 2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード