6OHG

Structure of Plasmodium falciparum vaccine candidate Pfs230D1M in complex with the Fab of a transmission blocking antibody

6OHG の概要

• エントリーDOI: 10.2210/pdb6ohg/pdb
• 分子名称: Gametocyte surface protein P230, 4F12 Light Chain, 4F12 Heavy chain, ... (9 entities in total)
• 機能のキーワード: malaria, transmission blocking, sexual stage, 6 cysteine-rich pfs230, immune system
• 由来する生物種: Plasmodium falciparum; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 71554.18

構造登録者

Garboczi, D.N.,Singh, K.,Gittis, A.G. (登録日: 2019-04-05, 公開日: 2020-06-17, 最終更新日: 2021-03-31)

• 主引用文献: Singh, K.,Burkhardt, M.,Nakuchima, S.,Herrera, R.,Muratova, O.,Gittis, A.G.,Kelnhofer, E.,Reiter, K.,Smelkinson, M.,Veltri, D.,Swihart, B.J.,Shimp Jr., R.,Nguyen, V.,Zhang, B.,MacDonald, N.J.,Duffy, P.E.,Garboczi, D.N.,Narum, D.L.; Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins.; Commun Biol, 3:395-395, 2020; PubMed: 32709983; DOI: 10.1038/s42003-020-01123-9

実験手法

X-RAY DIFFRACTION (2.385 Å)