In situ structure of Rotavirus RNA-dependent RNA polymerase at transcript-elongated state

Summary for 6OGZ

EMDB information20060 20059
DescriptorRNA (5'-R(P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3'), RNA (5'-R(P*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3'), RNA-dependent RNA polymerase of rotavirus A, ... (6 entities in total)
Functional Keywordsrna-dependent rna polymerase, capsid shell protein, transcription, in situ structure, rotavirus, transcriptional factors, reovirus, virus, viral protein-rna-transferase complex, viral protein/rna/transferase
Biological sourceRotavirus A
Total number of polymer chains13
Total molecular weight1171584.16
Ding, K.,Chang, T.,Shen, W.,Roy, P.,Zhou, Z.H. (deposition date: 2019-04-03, release date: 2019-05-22, Last modification date: 2019-12-18)
Primary citation
Ding, K.,Celma, C.C.,Zhang, X.,Chang, T.,Shen, W.,Atanasov, I.,Roy, P.,Zhou, Z.H.
In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release.
Nat Commun, 10:2216-2216, 2019
PubMed: 31101900 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-10236-7
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone50 0.1% 0.46MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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