6OGX
Ternary complex of OX40R (TNFRSF4) bound to Fab1 and Fab2
Summary for 6OGX
Entry DOI | 10.2210/pdb6ogx/pdb |
Descriptor | Fab 1 Heavy Chain, Fab1 Light Chain, Tumor necrosis factor receptor superfamily member 4, ... (7 entities in total) |
Functional Keywords | tnfrsf4, cd134, ox40r, fab, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 112763.66 |
Authors | Ultsch, M.H.,Boenig, G.,Harris, S.F. (deposition date: 2019-04-03, release date: 2019-07-10, Last modification date: 2020-07-29) |
Primary citation | Yang, Y.,Yeh, S.H.,Madireddi, S.,Matochko, W.L.,Gu, C.,Pacheco Sanchez, P.,Ultsch, M.,De Leon Boenig, G.,Harris, S.F.,Leonard, B.,Scales, S.J.,Zhu, J.W.,Christensen, E.,Hang, J.Q.,Brezski, R.J.,Marsters, S.,Ashkenazi, A.,Sukumaran, S.,Chiu, H.,Cubas, R.,Kim, J.M.,Lazar, G.A. Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members. Mabs, 11:996-1011, 2019 Cited by PubMed: 31156033DOI: 10.1080/19420862.2019.1625662 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.77 Å) |
Structure validation
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