Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, post-state

Summary for 6OG2

Related6OG1 6OG3 6OAX 6OAY
EMDB information20050 20049 20051 20004 20005
DescriptorHyperactive disaggregase ClpB, ADENOSINE-5'-DIPHOSPHATE (2 entities in total)
Functional Keywordsdisaggregase, clpb, aaa+, chaperone
Biological sourceEscherichia coli K-12
Total number of polymer chains2
Total molecular weight195318.54
Rizo, A.R.,Lin, J.-B.,Gates, S.N.,Tse, E.,Bart, S.M.,Castellano, L.M.,Dimaio, F.,Shorter, J.,Southworth, D.R. (deposition date: 2019-04-01, release date: 2019-06-12, Last modification date: 2019-06-19)
Primary citation
Rizo, A.N.,Lin, J.,Gates, S.N.,Tse, E.,Bart, S.M.,Castellano, L.M.,DiMaio, F.,Shorter, J.,Southworth, D.R.
Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10:2393-2393, 2019
PubMed: 31160557 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-10150-y
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers12 0.2% 0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures