6OE4

Prefusion RSV F monomer bound by neutralizing antibody CR9501

6OE4 の概要

• エントリーDOI: 10.2210/pdb6oe4/pdb
• 分子名称: Fusion glycoprotein F0, CR9501 Fab Light Chain, CR9501 Fab Heavy Chain, ... (4 entities in total)
• 機能のキーワード: class i fusion protein, immunoglobulin, respiratory syncytial virus, trimerization, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human respiratory syncytial virus A (strain A2); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 212045.98

構造登録者

McLellan, J.S.,Gilman, M.S.A. (登録日: 2019-03-27, 公開日: 2019-04-17, 最終更新日: 2020-01-01)

• 主引用文献: Gilman, M.S.A.,Furmanova-Hollenstein, P.,Pascual, G.,B van 't Wout, A.,Langedijk, J.P.M.,McLellan, J.S.; Transient opening of trimeric prefusion RSV F proteins.; Nat Commun, 10:2105-2105, 2019; PubMed: 31068578; DOI: 10.1038/s41467-019-09807-5

実験手法

X-RAY DIFFRACTION (3.3 Å)