6ODG

SVQIVY, Crystal Structure of a tau protein fragment

Summary for 6ODG

Entry DOI	10.2210/pdb6odg/pdb
Descriptor	Microtubule-associated protein tau (2 entities in total)
Functional Keywords	amyloid, tau, microed, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	1415.63
Authors	Eisenberg, D.S.,Boyer, D.R.,Sawaya, M.R.,Seidler, P.M. (deposition date: 2019-03-26, release date: 2019-10-02, Last modification date: 2024-03-13)
Primary citation	Seidler, P.M.,Boyer, D.R.,Murray, K.A.,Yang, T.P.,Bentzel, M.,Sawaya, M.R.,Rosenberg, G.,Cascio, D.,Williams, C.K.,Newell, K.L.,Ghetti, B.,DeTure, M.A.,Dickson, D.W.,Vinters, H.V.,Eisenberg, D.S. Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. J.Biol.Chem., 294:16451-16464, 2019 Cited by PubMed: 31537646 DOI: 10.1074/jbc.RA119.009688 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1 Å)

Structure validation