6OBX
Montbretin A analogue M10-MbA in complex with Human pancreatic alpha-amylase
Summary for 6OBX
Entry DOI | 10.2210/pdb6obx/pdb |
Descriptor | Pancreatic alpha-amylase, CHLORIDE ION, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | amylase, diabetes, obesity, glucosyl hydrolase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 57030.86 |
Authors | Caner, S.,Brayer, G.D. (deposition date: 2019-03-21, release date: 2020-02-12, Last modification date: 2023-10-11) |
Primary citation | Tysoe, C.R.,Caner, S.,Calvert, M.B.,Win-Mason, A.,Brayer, G.D.,Withers, S.G. Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic alpha-amylase. Chem Sci, 10:11073-11077, 2019 Cited by PubMed: 32206255DOI: 10.1039/c9sc02610j PDB entries with the same primary citation |
Experimental method |
Structure validation
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